Very premature pubarche in girls is not a pubertal variant
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چکیده
منابع مشابه
Very premature pubarche in girls is not a pubertal variant.
Premature pubarche (PP) in girls is considered to be a benign phenomenon and is the clinical expression of premature adrenarche. Since it does not usually increase the risk of either abnormalities in pubertal development or a reduced final adult height, a non-interventional approach is generally adopted after exclusion of non-classical (NC)congenital adrenal hyperplasia (CAH). Extremely prematu...
متن کامل[Premature pubarche].
Premature adrenarche refers to the appearance of public hair before age 8 years in girls and 9 years in boys, without other signs of puberty or virilization. Growth velocity may be increased and slightly advanced bone maturation is often present and is usually well correlated with the height age. The transient acceleraration of growth and of bone maturation have no negative effects on the onset...
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Premature pubarche can be benign, or it can be an early marker of insulin resistance in some girls. The aim of this study was to evaluate insulin resistance in prepubertal girls presenting with premature pubarche (n = 19; mean age = 6.93 +/- 1.78) as compared to age- and Tanner stage-matched controls (n = 10; mean age = 7.55 +/- 1.32) using indirect insulin resistance parameters. Two groups wer...
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Two young girls with hirsutism and premature pubarche showed nonclassical 3 beta-hydroxysteroid dehydrogenase (3 beta-HSD) deficiency. Post-ACTH increased serum delta 5-17-hydroxypregnenolone and increased ratio of delta 5-17-hydroxypregnenolone/17-hydroxyprogesterone are the most sensitive indicators of nonclassical 3 beta-HSD deficiency. Nonclassical 3 beta-HSD deficiency may not be uncommon,...
متن کاملPremature pubarche in an infant: nonclassical congenital adrenal hyperplasia or mini-puberty variant?
A previously healthy, 7-mo-old male infant presented with a 3-mo history of pubic hair. He was a healthy, term newborn who was born to nonconsanguineous parents, and had appropriate weight and length. Physical examination revealed thick and long pubic hair on the scrotum, without hyperpigmentation or enlargement of the penis (Fig. 1a). No other signs of virilization or secondary sexual developm...
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ژورنال
عنوان ژورنال: HORMONES
سال: 2012
ISSN: 1109-3099
DOI: 10.14310/horm.2002.1365